IUI is a simple form of treatment where prepared sperm is placed inside the uterine cavity. There may be some administration of fertility drugs to increase the chances of success. However, IUI can also occur in a natural cycle (i.e. no drug support).
In a stimulated cycle, satisfactory development of follicles will be monitored via blood tests and ultrasounds. If required, ovulation will be triggered with an injection of human Chorionic Gonadotrophin (hCG). This will induce the release of the eggs, at which stage the male partner is asked to produce a semen sample (donor sperm may be used when required). The semen is then prepared in the laboratory before being deposited into the uterus via a thin catheter. A natural cycle involves the monitoring of follicular development. Once ovulation has been detected, insemination can occur.