The fertility drug protocols for GIFT are identical to those used for IVF/ICSI. The main difference is in the retrieval and transfer procedures. The eggs are generally collected laparoscopically and up to three eggs are mixed with a prepared sample of sperm and then placed into the fallopian tube under direct vision.
In zygote intrafallopian transfer, up to three fertilised eggs (pro-nucleate stage) are transferred to the fallopian tube laparoscopically. Any excess embryos may be frozen for future use.